毛喉素

[CAS號] 66428-89-5
[分子式] C22H34O7
[分子量] 410.51
[溶解度]溶於乙醇，氯仿和DMSO等有機溶劑
[植物來源] forleus forskohlii（威爾士）。
[外觀]淺黃色粉末
[藥理作用]減肥，塑身。
關於福斯科林
Forskolin is a diterpene derivative derived from the activation of adenylate cyclase by the plant larynx.福斯高林是一種二萜衍生物，由植物喉腺激活腺苷酸環化酶而衍生。 It is a hydrophobic activator that stimulates adenylate cyclase activity in mammalian cells.它是一種疏水性激活劑，可刺激哺乳動物細胞中的腺苷酸環化酶活性。 The anti-inflammatory and anti-oxidative effects of forskolin are due to inhibition of macrophage activation, thereby reducing the levels of thromboxane B2 and superoxide.毛喉素的抗炎和抗氧化作用歸因於巨噬細胞活化的抑制，從而降低了血栓烷BXNUMX和超氧化物的水平。 This property makes forskolin an effective drug for the treatment of heart disease, high blood pressure, diabetes and asthma.此特性使福司可林成為治療心髒病，高血壓，糖尿病和哮喘的有效藥物。 In vitro experiments showed that the activation of adenylate cyclase by Forskolin resulted in a significant increase in cyclic AMP levels in a variety of eukaryotic cells.體外實驗表明，福斯可林對腺苷酸環化酶的激活導致各種真核細胞中環AMP含量的顯著增加。 The low concentration of forskolin can increase the intracellular cyclic AMP in a small amount by enhancing the activation of adenylate cyclase in intact cells.低濃度的佛司可林可以通過增強完整細胞中腺苷酸環化酶的活化來少量增加細胞內環狀AMP。