癌細胞組成的植物

Wogonin導致腫瘤細胞的死亡程序凋亡,而對健康細胞幾乎沒有影響。 Scientists from the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have found the molecular mechanism underlying this selectivity.德國癌症研究中心(Deutsches Krebsforschungszentrum,DKFZ)的科學家發現了這種選擇性的分子機制。 The mechanism underlying the selective effect of this plant constituent had still been unclear.尚不清楚該植物成分的選擇性作用的機制。 There are two different ways by which the apoptosis program can be started in a cell: by external stimuli or by signals from within the cell as a response to factors such as radioactive radiation or reactive oxygen compounds such as hydrogen peroxide (H2O2).可以通過兩種不同的方法在細胞中啟動凋亡程序:通過外部刺激或通過細胞內的信號作為對諸如放射性輻射或諸如過氧化氫(HXNUMXOXNUMX)等活性氧化合物的響應。 Defects in genes that control growth can turn a cell into a threat for the whole organism.控制生長的基因缺陷可以將細胞變成對整個生物體的威脅。 Defective cells that might get out of control are driven into suicide by a protective mechanism called apoptosis.可能失控的缺陷細胞被稱為凋亡的保護機制驅使自殺。 However, this life saving mechanism is no longer working in most tumor cells, since numerous molecules regulating apoptosis are defective.然而,由於許多調節細胞凋亡的分子是有缺陷的,因此這種挽救生命的機制在大多數腫瘤細胞中不再起作用。