土黴素

[CAS號] 79-57-2 
[分子式] C22H24N2O9 
[分子量] 460.434
[外觀]米色至淺黃色結晶性粉末
[用途]動物藥品 
關於土黴素
Oxytetracycline is an anti-inflammatory, antibiotic, and anti-proliferative agent shown to inhibit mitochondrial protein synthesis.土黴素是一種抗炎藥，抗生素和抗增殖藥，可抑制線粒體蛋白質的合成。 Mechanistic studies show that this compound reduces cytochrome c activity which eventually causes cell growth arrest.機理研究表明，該化合物降低了細胞色素c的活性，最終導致細胞生長停滯。 Additionally, Oxytetracycline has demonstrated the ability to reduce murine bronchial inflammation.另外，土黴素已顯示出減少鼠支氣管炎症的能力。 The anti-inflammatory characteristics of this agent are due to its ability to cause a decrease in IL-4, IL-5, IL-13, immune cells, and the ovalbumin-specific IgE.該藥物的抗炎特性是由於其引起IL-XNUMX，IL-XNUMX，IL-XNUMX，免疫細胞和卵清蛋白特異性IgE降低的能力。 Data suggests that Oxytetracycline is also an inhibitor of NF-κB activation via phosphorylation and degradation of IκB-α.數據表明土黴素也是通過IκB-α的磷酸化和降解來抑制NF-κB活化的抑製劑。
Oxytetracycline works by interfering with the ability of bacteria to produce essential proteins.土黴素通過乾擾細菌產生必需蛋白質的能力起作用。 Without these proteins, the bacteria cannot grow, multiply and increase in numbers.沒有這些蛋白質，細菌就無法生長，繁殖和增加數量。