氯法拉濱

[ 系統學 (IUPAC) 名稱 ] 5-(6-amino-2-chloro-purin-9-yl) -4-fluoro-2- (hydroxymethyl)oxolan-3-ol
[CAS號] 123318-82-1
[ 分子式 ] C10HClFN5O3 
[分子量] 303.677
關於氯法拉濱
Clofarabine is a purine nucleoside antimetabolite marketed in the US and Canada as Clolar.氯法拉濱是一種嘌呤核苷抗代謝藥，在美國和加拿大以Clolar銷售。 In Europe and Australia/New Zealand the product is marketed under the name Evoltra.在歐洲和澳大利亞/新西蘭，該產品以Evoltra的名稱銷售。 It is FDA-approved for treating a type of leukaemia called relapsed or refractory acute lymphoblastic leukaemia (ALL) in children, after at least two other types of treatment have failed.經過至少兩種其他類型的治療失敗後，它已獲得FDA批准，可用於治療兒童中一種稱為複發性或難治性急性淋巴細胞白血病（ALL）的白血病。 It is not known if it extends life expectancy.不知道它是否可以延長預期壽命。 Some investigations of effectiveness in cases of acute myeloid leukaemia (AML) and juvenile myelomonocytic leukaemia (JMML) have been carried out.已經對急性髓細胞性白血病（AML）和青少年骨髓單核細胞性白血病（JMML）病例的有效性進行了一些研究。 Ongoing trials are assessing its efficacy, if any, for managing other cancers.正在進行的試驗正在評估其治療其他癌症的效力（如果有）。